The study emphasizes predictors for atopic dermatitis torches with machine learning

The duration, frequency and severity of atopic dermatitis torches predict the future severity of atopic dermatitis that recent knowledge of mechanical learning and these elements are also associated with a reduced quality of life.¹

This data resulted from a study that was carried out to validate the predictability of torches and the severity of dermatitis in the atopes of the predictive variables. This analysis was led by researchers such as Mia-Louise Nielsen, MSC, PhD, from the Department of Dermatology at Copenhagen University Hospital-Bispebjerg in Denmark.

While it has been shown that systemic medicines are effective in the treatment of atopic dermatitis, Nielsen et al.²

“In particular, patients with mild to moderate diseases, but persistent flickering and an unstable course of the disease can be at risk,” wrote Nielsen and Co authors.^1.3 “This study used statistical methods and predictive models for machine learning to validate the predictability and to identify predictors for torches and severity of the disease.”

Experimental design and findings

The examination team used a comprehensive data set from the Danish skin cohort, the content of which highlights records on adults in Denmark with atopic dermatitis. This data also includes information on the severity of the disease and about patterns in connection with torches. The team examined these results in order to examine connections between the frequency of torches in such patients in 2022 and the self -reported severity of these patients in 2023.

Nielsen and colleagues used quantile regression models to evaluate this relationship. They implemented increased random forest algorithms with the aim of identifying important predictive variables of both the annual flare frequency and the severity of atopic dermatitis. People who had received a dermatologist confirmed during their adulthood were justified as justified for the involvement of the researchers.

At 2 times, Nielsen et al. From January 14 to February 6, 2022 and from January 3 to January 31, 2023. Your surveys have been developed to record general data in patients such as age, gender and comorbid conditions and to capture specific information in connection with their atopic dermatitis. The examination team completed its research after rating 878 participants, all of whom had an average age of 49.0 years (Interquartile range [IQR]39.0–59.0 years).

Among the 878 subjects, 26 reported that he had no atopic dermatitis flares in 2022.¹ In addition, 405 reported between 1 and 5 disease torches, 169 reported 6 – 10 torches, and 278 reported more than 10 torches in the same year. In the results of the researchers' quantile regression, the data showed a significant connection between the number of torches in 2022 and several patients with patients reported in 2023.

Even after adapting the basic values for the patient-oriented assessment of atopic dermatitis (PO-Scorad), the flare frequency remained significantly connected to the values for patient-oriented eczema (poem) and the Dermatology Life Quality Index (DLQI).¹

In addition, the analysis of Nielsen and colleagues later showed that the torch properties – duration, frequency and severity – were among the strongest predictors to the general seriousness of the patient's illness. They also came to the conclusion that the severity of atopic dermatitis itself turned out to be a key factor for the prediction, as studying providers reported every year.

Overall, this study showed that the self -reported number of torches in the previous year as well as duration and severity of the disease predict in the future in topical dermatitis.

“Although a consensus about how many torches are still to be determined, the current findings indicate that torches could serve as an early indicator of the progression of the disease or the inadequate disease control, which emphasizes that torches for clinical decision -making to support optimal treatment strategies could be relevant,” concluded the investigators.¹

References

1. Nielsen M., Nymand LK, Pena ad, et al. Predictors for torches and severity of the disease in patients with atopic dermatitis using machine more. Jama Dermatol. Online published online on July 16, 2025. DOI: 10.1001/Jamermatol.2025.2073.

2. Charming CR, Venn AJ, Williams HC. The patient-oriented eczema measure: development and initial validation of a new instrument to measure the severity of eczema from the patient from the perspective of the patient. Arch dermatol. 2004; 140 (12): 1513-1519. DOI: 10.1001/Archderm.140.12.1513.

3. Wei W, Anderson P, Gadkari a, et al. The scope and consequences of inadequate disease control in adults with moderate to severe atopic dermatitis. J Dermatol. 2018; 45 (2): 150-157. DOI: 10.1111/1346-8138.14116.