The increase in GI cancer in the early debut emphasizes the screening gap

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Early gastrointestinal cancer (GI) rise worldwide and have become the fastest growing category of early cancer in the United States, with breast cancer. According to two literature overview, which recently cited by researchers from the Dana-Farber Cancer, this increase includes colorectal, stomach, pancreas and esophageal cancer.

The first evaluation, published in Jamaoffers an overview of the current understanding of early-on-gi cancer species as GI cancer that was diagnosed before the age of 50. However, the authors find that during colon cancer, more than 50% of early GI cases of early-on-gi cases are more and more common in younger population groups in this category.

Among the GI cancer discussed currently only has colon cancer for screening guidelines for people with average risk in the United States. Recommendations now recommend screening from the age of 45. However, national data from 2021 suggest that compliance remains low: Less than 1 out of 5 US -growing ages between the ages of 4 and 49, colon cancer screening has been subjected to this year.

Differences and old trends

A second rating, published in the British Journal of Surgeryconcentrated on incidence trends from 2010 to 2019. In the period, it was found by 14.8% by 14.8% of the early GI diagnoses of GI cancer, with some of the steepest increases in people between the ages of 15 and 39.

The burden of early use GI cancer is not evenly distributed. The review showed that people who are black, Hispanic, indigenous ancestors and women are disproportionately affected. In addition, people who were born in 1990 suffer twice as likely that colorectal cancer and four times as likely get rectal cancer than the people born in 1950.

The latest data from the centers for the control and prevention of diseases reinforce this trend. The incidence of colon cancer in people between the ages of 15 and 19 has more than tripled and has almost doubled in the 20 to 24 years.

The authors of both reviews underline the importance of improving the screening rates, especially among younger adults, who may not be at risk. They also emphasize the need to tackle differences in terms of cancer treatment and the results of the affected population groups.

Reference: Jayakrishnan T, NG K. Early upstream gastrointestinal cancer. Jama. 2025. Doi: 10.1001/Jama.2025.10218

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